The evolution of a universal genetic code
نویسندگان
چکیده
منابع مشابه
Origin and evolution of the genetic code: the universal enigma.
The genetic code is nearly universal, and the arrangement of the codons in the standard codon table is highly nonrandom. The three main concepts on the origin and evolution of the code are the stereochemical theory, according to which codon assignments are dictated by physicochemical affinity between amino acids and the cognate codons (anticodons); the coevolution theory, which posits that the ...
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15 صفحه اولThe Early Evolution of the Genetic Code
first genetic material may have used a simpler backbone than ribose. One candidate is peptide nucleic acid (PNA), in which the backbone is polymeric N-(2-amino-ethyl)glycine (AEG) and the N-acetic acids of the bases Evolutionary inferences rely on diversity. The source of (N 9 for purines, N 1 for pyrimidines) are linked via amide differences among organisms is accumulated diver-bonds (Figure 1...
متن کاملAlgebraic Evolution of the Genetic Code
The evolution of the genetic code has been speculated by many authors, but all of them lack determinative proofs. Jukes [4] inferred the evolution from mitochondrial codes, which are different from the universal codes in some respects. He postulated an archetypal code containing 14 amino acids, from which the universal code could evolve by gene duplication followed by mutational changes. This p...
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The genetic code is not quite universal. The rare variations that we know of reveal selective pressures on the code and on the translation machinery. New data suggest the code changes through ambiguous intermediates and that termination is context dependent.
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1976
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.73.7.2336